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Sartorius AG octet analysis studio 12 2
a BLI sensorgrams showing the binding curves of recombinant human GADD45β (rhGADD45β) at indicated concentrations to recombinant human RIPK3 (rhRIPK3). b Graphical summary of kinetic parameters and apparent affinity constants (KD) derived from BLI experiments, analysed using Octet Analysis Studio 12.2.
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a BLI sensorgrams showing the binding curves of recombinant human GADD45β (rhGADD45β) at indicated concentrations to recombinant human RIPK3 (rhRIPK3). b Graphical summary of kinetic parameters and apparent affinity constants (KD) derived from BLI experiments, analysed using Octet Analysis Studio 12.2.

Journal: Cell Death Discovery

Article Title: GADD45β inhibits RIPK3-mediated NF-κB activation by interfering with NEMO-RIPK1-RIPK3 interactions

doi: 10.1038/s41420-025-02894-y

Figure Lengend Snippet: a BLI sensorgrams showing the binding curves of recombinant human GADD45β (rhGADD45β) at indicated concentrations to recombinant human RIPK3 (rhRIPK3). b Graphical summary of kinetic parameters and apparent affinity constants (KD) derived from BLI experiments, analysed using Octet Analysis Studio 12.2.

Article Snippet: All mathematical manipulations and fitting were performed using the Octet Analysis Studio 12.2 from Sartorius.

Techniques: Binding Assay, Recombinant, Derivative Assay